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超加工食品和高敏感性C反应蛋白

Kevin Sajan1, Nishi Anthireddy2, Alexandra Matarazzo3

  • 1M2 Geisinger Commonwealth School of Medicine.

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概括

超加工食品的高消费与高灵敏性C反应蛋白 (hs-CRP) 水平的升高有关,这是炎症和心血管疾病风险的标志物. 这一发现突显了加工食品的健康影响.

关键词:
心血管疾病风险高灵敏度c反应蛋白超加工食品

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科学领域:

  • 营养科学
  • 心血管健康
  • 炎症生物标志物

背景情况:

  • 超加工食品在西方饮食中普遍存在.
  • 高灵敏性C反应蛋白 (hs-CRP) 是一种主要的炎症标志物和心血管疾病 (CVD) 的预测因子.
  • 需要对代表性群体进行进一步的研究,以确定UPF消耗与hs-CRP之间的关联.

研究的目的:

  • 确定超加工食品的增加是否与显著增加的hs-CRP水平有关.
  • 分析来自UPF和hs-CRP能量摄入的不同百分比之间的关系.
  • 评估UPF消费对炎症的临床和公共卫生影响.

主要方法:

  • 利用美国国家健康和营养检查调查的9254名参与者的数据.
  • 使用NOVA分类系统,量化超加工食品的摄入量占总能量的百分比.
  • 使用后勤回归分析, 调整年龄,性别,吸烟和体力活动等因素.

主要成果:

  • 摄入量最高的人 (60-79%的能量摄入量) 显示hs-CRP水平显著增加 (RR=1.11).
  • 在那些从UPF消耗40-59%能量的人群中也观察到hs-CRP的显著增加 (RR=1.14).
  • 20-39%的UPF摄入量没有显著增加,而最低四分位数 (0-19%) 作为参考.

结论:

  • 这项研究表明,在一个大型的代表性美国样本中,高超加工食品消费与高hs-CRP水平之间存在显著的关联.
  • 这些发现强调了UPF在促进炎症和增加心血管疾病风险方面的潜在作用.
  • 结果对公共卫生政策,临床实践以及对饮食模式和慢性疾病的未来研究有重大影响.