在白内障手术中,内腔利多卡因可以减轻疼痛,但只有很少.
在PubMed上查看摘要
概括
此摘要是机器生成的。在白内障手术期间,内腔利多卡因可轻微缓解疼痛. 这种疼痛缓解在近视患者中最为明显.
科学领域
- 眼科 眼科
- 手术麻醉
- 临床试验
背景情况
- 眼手术是一种常见的手术.
- 在白内障手术期间疼痛管理对于患者的舒适至关重要.
- 内腔麻醉是一种疼痛控制的选择.
研究的目的
- 评估室内利多卡因在例行白内障手术期间减轻疼痛的疗效.
- 在接受室内利多卡因和对照溶液的患者之间比较疼痛水平.
- 确定患者在手术过程中感知疼痛的因素.
主要方法
- 进行了一项前性,单盲,随机对照试验.
- 成年患者接受了发酵性白内障提取,随机分别接受室内利多卡因或平衡盐溶液.
- 在两个关键时间点 (注射和手术完成) 评估疼痛.
主要成果
- 与对照组相比,利多卡因组的整体疼痛评分显著降低 (0. 43/10).
- 较近视的患者比较少近视的患者有更大的疼痛 (1. 80/10).
- 没有观察到注射时疼痛的显著差异,也没有观察到术后视力敏度的差异.
结论
- 在白内障手术期间,内腔利多卡因提供了统计学上显著但适度的疼痛缓解.
- 在近视患者中,室内利多卡因的止痛作用更为明显.
- 进一步的研究可能会探索优化室内麻醉以提高患者舒适度.
相关概念视频
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...

