使用一种新的非侵入性诊断方法,促进肺高血压的早期诊断
Rieta Aben1, Timothy Burton2, Farhad Fathieh2
1Atrium Health Navicent, Macon, Georgia, USA.
JACC. Case reports
|September 5, 2025
概括
肺高血压 (POC-PH) 的新疗点测试有助于诊断心声回声无断的情况. 这种新型工具在诊断肺高血压时具有临床实用性,即使传统方法失败.
科学领域:
- 心脏病学
- 肺部医学
- 诊断成像
背景情况:
- 肺高血压 (PH) 的诊断往往由于胸腔回声图 (TTE) 的局限性而延迟,特别是当三回速度 (TRV) 无法测量时.
- 目前肺动脉高血压的诊断延迟时间平均为两年,需要多次TTE.
- 康维斯塔PH系统 (POC-PH) 是FDA批准的诊断工具,旨在解决这些局限性.
研究的目的:
- 评估CorVista PH (POC-PH) 诊断测试的临床效用.
- 评估POC-PH在确定TTE不足时的肺高血压 (PH) 的有效性.
- 展示POC-PH在PH诊断和进一步管理中的作用.
主要方法:
- 一个最初未被诊断的PH患者通过多个TTEs的病例报告.
- 使用CorVista PH (POC-PH) 临床测试进行初始PH查.
- 在所述病例中进行了右心导管检查 (RHC),以确定PH诊断和表型.
主要成果:
- POC-PH测试确定了先前TTEs负的患者的PH,导致RHC和2组PH的诊断 (心力衰竭与保留的喷射分数).
- 另外3名具有可测量的TRV的患者在POC-PH检测中呈阳性,随后的RHC证实了毛囊前和毛囊后PH表型.
- 在识别高平均肺动脉压力时,POC-PH显示了82%的灵敏度和92%的特异性.
结论:
- 科尔维斯塔PH (POC-PH) 测试在检测TTE可能不确定的或未能引起怀疑的肺高血压方面具有显著的临床效用.
- POC-PH可以加快PH的诊断途径,可能减少诊断延迟.
- 这种点的护理工具有助于识别各种PH表型,促进及时和适当的患者管理.
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