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研究领域生物医学和临床科学瘤学和致癌症预测和预后标志物
在非小细胞肺癌患者中脑转移的成像利用和治疗模式:SEER-Medicare和SEER数据库分析

在非小细胞肺癌患者中脑转移的成像利用和治疗模式:SEER-Medicare和SEER数据库分析

Mark D Danese ¹, Jason Shafrin ², Melissa Laurie ³, Beata Korytowsky ³, Shane Jordan ³, Debbie Ryan ³, Sukhmani K Padda ⁴

Mark D Danese ¹, Jason Shafrin ², Melissa Laurie ³

¹Outcomes Insights, Inc., Calabasas, CA.
²Center for Healthcare Economics and Policy, FTI Consulting, Los Angeles, CA.
³Mirati Therapeutics, a Bristol Myers Squibb Company, San Diego, CA.
⁴Fox Chase Cancer Center, Temple Health, Philadelphia, PA.

⁰Outcomes Insights, Inc., Calabasas, CA.

Clinical Lung Cancer +

|

2025年九月5日

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在PubMed上查看摘要

概括

此摘要是机器生成的。

超过20%的转移性非小细胞肺癌 (mNSCLC) 患者在诊断时有大脑转移. 许多患者未能接受建议的脑部成像,

科学领域

癌症学
放射学
医疗服务研究

背景情况

大脑转移是转移性非小细胞肺癌 (mNSCLC) 的重要问题.
目前的指导方针建议对mNSCLC进行基线脑部成像.
了解诊断和治疗的流行和差异至关重要.

研究的目的

确定患有mNSCLC的医疗保险受益人的大脑转移的发生率.
分析大脑成像和第一线系统治疗的利用.
确定大脑成像和治疗的预测因素,重点关注年龄和社会经济因素.

主要方法

使用与医疗保险索赔相关的监测,流行病学和最终结果 (SEER) 数据 (2015-2019).
对6860名被诊断患有mNSCLC的医疗保险受益者进行了检查.
使用后勤回归来评估脑成像和一线系统治疗的预测因素.

主要成果

在诊断时,已知有21. 4%的患者患有脑转移.
27. 3% 的患者没有接受脑部成像诊断.
老年患者和贫困地区的患者接受脑部成像或第一线治疗的可能性较低.

结论

在诊断时脑转移是常见的mNSCLC患者.
特别是在弱势群体中,推的大脑成像技术的使用量显著不足.
阶段和治疗的差异凸显了提供公平医疗服务的需要.

关键词:

大脑成像诊断情况医疗保健中的差异在 NSCLC 在现实世界

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