基于深度学习的多组学模型用于结直肠癌术后远程转移的风险分层
Xiuzhen Yao1, Xiaoyu Han2, Danjiang Huang3
1Department of Ultrasound, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China (X.Y.).
Academic radiology
|September 5, 2025
概括
深度学习模型在手术后准确预测结直肠癌患者的远程转移. 这些先进的诺米图模型有效地分层了无病生存风险,改善了患者的预后评估.
科学领域:
- 癌症学
- 医学成像
- 人工智能
背景情况:
- 结肠直肠癌 (CRC) 在预测术后远程转移 (DM) 和生存方面具有重大挑战.
- 准确的预后对于定制治疗策略和改善患者的结果至关重要.
研究的目的:
- 开发和验证基于深度学习的多态模型,用于预测CRC患者的DM.
- 评估这些模型在评估生存预后和分层风险方面的有效性.
主要方法:
- 对521名手术前CT和手术后组织病理学数据的回顾性分析.
- 使用ResNet-101骨干开发深度学习放射学 (DLRS) 和深度学习病理学 (DLPS) 模型.
- 将放射性和病理特征整合到两个预测和风险分层的诺莫格拉姆模型中.
主要成果:
- 深度学习模型 (DLRS,DLPS) 实现了DM的高预测性能 (AUC> 0.91).
- 与传统模型相比,集成的诺姆图模型显示出更高的准确性 (AUC> 0. 93).
- 在卡普兰-梅尔分析中,诺米图有效地分层了3年无病生存期 (DFS).
结论:
- 基于深度学习的多态模型在CRC中提供高准确度的术后DM预测.
- 诺莫格拉姆模型提供了可靠的DFS风险分层,有助于CRC患者的临床决策.
更多相关视频
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
372
07:13Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
Published on: April 18, 2025
193
相关概念视频
01:21Inflammatory Bowel Disease V: Surgical Management
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
01:26Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...