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Updated: Sep 8, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
09:04

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Published on: May 22, 2014

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类型A胆固醇依赖性细胞酶转移到跨戈尔吉网络以激活NLRP3炎症体

Nanyang Xiao1, Airi Kogishi1, Lisa Radochonski1,2

  • 1Department of Microbiology, University of Chicago, Chicago, IL, USA.

Nature immunology
|September 5, 2025
PubMed
概括

胆固醇依赖性细胞酶 (CDC) 重塑跨戈尔吉网络 (TGN),以激活NLRP3炎症体. 这种细菌毒素机制与毛孔形成不同,涉及免疫反应的细胞内器官操纵.

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