在多发性硬化症中与性别和种族身份相关的延迟诊断的横截面研究
Amy Li Safadi1, Brian D Barry2, Robert K Shin3
1Department of Neurology, Inova Health System, Fairfax, VA, USA. Amy.Safadi@inova.org.
Journal of racial and ethnic health disparities
|September 5, 2025
概括
患有多发性硬化症 (MS) 的男性和黑人患者在诊断方面遇到延迟. 男人面临更长的评估-诊断时间,而黑人患者则延迟了初次神经病诊,影响了MS护理.
科学领域:
- 神经学
- 临床研究
- 健康上的差异
背景情况:
- 之前的研究表明男性和黑人患有多发性硬化症的预后较差.
- 诊断和评估延迟导致这些差异的作用仍未得到充分研究.
研究的目的:
- 调查男性和黑人患者多发性硬化症 (MS) 的评估和诊断的潜在延迟.
- 确定与延迟MS诊断和护理相关的人口因素.
主要方法:
- 在2019年至2021年期间在一个机构进行的基于调查的探索性研究.
- 对患有多发性硬化症 (pwMS) 的成年患者进行了关于症状发病,第一次神经科诊断和MS诊断时间表的调查.
主要成果:
- 与女性 (5 个月) 相比,男性从症状发作到MS诊断的中位延迟时间显著更长 (16. 5 个月).
- 与白人患者相比,患有多发性硬化症的黑人患者在症状出现和第一次神经科诊断之间延迟6个月的可能性更大.
- 在黑色和白色pwMS之间没有观察到显著的年龄差异,尽管男性在诊断时往往年龄较大.
结论:
- 在男性中观察到MS评估和诊断的显著延迟.
- 黑人pwMS在症状发作后出现神经评估延迟的可能性更高.
- 解决这些人口特异性延迟对于改善MS结果和健康公平至关重要.
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