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在实时运动追踪辐射治疗中,上腺转移和信任标志物以及呼吸阶段的补偿余额

Yuki Aoyama¹, Tetsuya Tomida², Susumu Nagata²

¹Radiation and Proton Therapy Center, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-Cho, Shizuoka, 411-8777, Japan. y.aoyama@scchr.jp.

Radiological physics and technology

|September 5, 2025

概括

这项研究量化了Synchrony治疗期间的信托标志物和上腺瘤的呼吸运动. 它提供了改善辐射精度和患者安全的基本建议.

科学领域:

辐射瘤学
医学成像
放射治疗物理

背景情况:

呼吸运动显著影响辐射治疗的准确性,例如信任标记 (FM) 和上腺转移.
高剂量处方需要精确的边际补偿来解释这一动作.
现有的文献缺乏关于呼吸阶段转移所需的具体数据.

研究的目的:

根据呼吸运动来确定和提出信任标记和上腺转移的最佳补偿边缘.
解决有关图像导向放射治疗中呼吸阶段转移边缘的知识差距.

主要方法:

使用四维计算机断层扫描 (4DCT) 和封闭式CT扫描,以检测FM和上腺转移的轮数据.
在4DCT图像中计算了FM和总瘤体积 (GTV) 中心之间的距离.
生成相对累积频率分布以导出右向左,后向前和上向下方向的边际值.

主要成果:

在所有三个主要方向上弥补呼吸位移的确定的边际值.
当FM在GTV中定位时,观察到高低保证金要求的减少.

结论:

这项研究为确定放射治疗中的运动适应边缘提供了关键数据.
这些发现支持对表现出显著呼吸运动的瘤进行改善的治疗计划.
建议可以提高对上腺损伤的高剂量放射治疗的安全性和有效性.

关键词:

上腺转移值得信赖的标记边际设置呼吸系统管理立体性身体辐射治疗

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