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相关概念视频

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Lysosomes are the site for the degradation of macromolecules and biological polymers released during membrane trafficking events such as secretory, endocytic, autophagic, and phagocytic pathways. The membrane-enclosed area of the lysosome, called the lumen, contains hydrolytic enzymes active in an acidic environment. These acid hydrolases are functional at a pH between 4.5 and 5 and are involved in cellular processes such as cell signaling, energy metabolism, restoration of the plasma membrane,...
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相关实验视频

Updated: Dec 30, 2025

Assessment and Communication for People with Disorders of Consciousness
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长期稳定,高分辨率的微电皮图脑计算机接口用于实时运动解码

Erda Zhou1,2, Xiner Wang1,2, Jizhi Liang1,2

  • 12020 X-Lab, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|September 6, 2025
PubMed
概括
此摘要是机器生成的。

这项研究引入了高密度微电皮质图 (μECoG) 脑计算机接口 (BCI) 以实现稳定,实时的运动解码. 这种灵活的BCI为神经疾病患者提供了更好的性能和更低的侵入性.

关键词:
大脑与计算机的接口灵活的合规微电机系统高分辨率微电皮质谱,实时电机解码

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相关实验视频

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Simultaneous Scalp Electroencephalography EEG, Electromyography EMG, and Whole-body Segmental Inertial Recording for Multi-modal Neural Decoding
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科学领域:

  • 神经科学
  • 生物医学工程
  • 医疗器械

背景情况:

  • 脑电脑接口 (BCI) 对于恢复神经障碍患者的沟通和运动功能至关重要.
  • 传统的皮质电图 (ECoG) BCI在空间分辨率和设备大小方面存在局限性.
  • 需要高密度的电极阵列来提高脑活动解码的精度.

研究的目的:

  • 开发和评估一个高分辨率,灵活的微电皮质谱 (μECoG) BCI系统.
  • 评估μECoG BCI的慢性稳定性和实时电机解码能力.
  • 展示μECoG技术的潜力,以克服传统ECoGBCI的局限性.

主要方法:

  • 使用微纳米制造创建灵活,高密度的μECoG电极阵列,电极密度增加了64倍.
  • 进行了203天的体内实验以评估慢性稳定性和性能.
  • 实现实时电机解码算法,用于游戏和光标控制等任务.

主要成果:

  • 在203天的时间里,μECoGBCI表现长期稳定.
  • 实现实时电机解码, 在训练7分钟内实现游戏控制.
  • 达到4. 15位/秒 (BPS) 的峰值比特率,可与无侵入性的皮质内EEGBCI相美.

结论:

  • 高分辨率的μECoGBCI提供了增强的空间特异性,以提高解码性能.
  • 灵活,高密度的μECoG阵列显著提升了BCI技术,减少了设备的大小和侵入性.
  • 这种μECoG BCI代表了灵活,高性能脑电脑接口的临床可行性的突破.