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Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

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Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
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自调节的水凝执行器

Taehun Chung1, Jaewon Choi1, Takafumi Enomoto2

  • 1Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH) 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk 37673, South Korea.

Chemical reviews
|September 6, 2025
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概括
此摘要是机器生成的。

这篇评论总结了自我调节的水凝,它们模仿生物系统以自主适应它们的行为. 这些智能软材料为先进的机器人和生物医疗设备提供了新的可能性.

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科学领域:

  • 材料科学
  • 软物质物理学
  • 生物仿真工程

背景情况:

  • 生物系统通过反机制表现出复杂的自我调节.
  • 凝是一种具有可调节性质的先进软材料.
  • 自主调节的水凝集成负反循环进行自主功能.

研究的目的:

  • 综合审查自调节水凝执行器的设计原则和实施策略.
  • 根据它们的调节模式 (持续与单循环) 来分类自调节水凝.
  • 突出这些水凝的机制,材料,燃料和应用.

主要方法:

  • 水凝调节类型的系统分类.
  • 分析潜在的机制,包括反循环.
  • 对各种水凝成分,化学燃料和性能指标的审查.

主要成果:

  • 自调节水凝可以分为持续调节和单周期调节.
  • 像振荡周期和振幅这样的关键参数受到水凝设计和燃料的影响.
  • 在软机器人,传感器和生物医疗设备中出现了多种应用.

结论:

  • 自调节的水凝执行器显示出适应性和智能材料系统的巨大潜力.
  • 需要进一步的研究来提高稳定性,模块化和实际应用.
  • 跨学科的努力可以加快基于水凝的先进监管系统的发展.