治疗肝硬化及其并发症的益生菌
Junxiu Chen1, Haonan Zhao1, Nahum Méndez-Sánchez2
1Department of Gastroenterology, General Hospital of Northern Theater Command, Teaching Hospital of Shenyang Pharmaceutical University, Shenyang, China; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Archives of medical research
|September 6, 2025
概括
益生菌可以通过改善肠道微生物组平衡来帮助治疗肝硬化及其并发症. 本综述探讨了它们对肝脏健康和肠肝轴调节的潜在益处.
科学领域:
- 胃肠病学和肝病学
- 微生物组研究
- 翻译医学
背景情况:
- 肝硬化是慢性肝病的晚期,会出现严重的并发症,如肝脏脑病和.
- 肠道微生物失调是肝硬化患者常见的发现,影响肠肝轴.
- 肠肝轴在肝硬化发展和进展中起着至关重要的作用.
研究的目的:
- 综合审查益生菌在治疗肝硬化方面的潜在疗效.
- 探索益生菌在缓解肝硬化相关并发症中的作用.
- 提供针对肠道微生物组进行肝病管理的见解.
主要方法:
- 对益生菌,肝硬化和肠道微生物组的文献综述.
- 对肝脏疾病中的肠肝轴现有研究的分析.
- 对肝硬化及其并发症的益生菌干预措施的综合证据.
主要成果:
- 肠道微生物失调与肝硬化发展和进展密切相关.
- 益生菌在肝硬化患者中具有调节肠道微生物组的潜力.
- 有证据表明益生菌可以帮助管理肝硬化相关的并发症.
结论:
- 益生菌是治疗肝硬化的一种有前途的疗法.
- 通过益生菌向肠道微生物组为治疗肝脏疾病提供了新的途径.
- 需要进一步研究以充分阐明益生菌在肝硬化治疗中的益处.
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