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Updated: Jul 8, 2026

Blastomere Explants to Test for Cell Fate Commitment During Embryonic Development
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咖啡酸乙破坏了Xenopus胚胎中的生殖层特征

Gang-Ho Yoon1, Myeoung Su Kim1, Sun-Cheol Choi1

  • 1Department of Biochemistry and Molecular Biology, Brain Korea 21 Project, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, South Korea.

Reproductive toxicology (Elmsford, N.Y.)
|September 6, 2025
PubMed
概括

咖啡酸乙 (CAPE) 通过激活FGF/MAPK通路来破坏脊椎动物的早期发育. 这种致病效应影响了Xenopus胚胎中的生殖层形成,体轴模式和细胞命运规范.

关键词:
美国农业局发展FGF的信号中皮形成神经模式类动物

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相关概念视频

Fertilization01:38

Fertilization

During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...