来自索马里的反动物对瑞克塞的暴露
Aamir M Osman1, Igor S Silito2, Ahmed A Hassan-Kadle3
1Graduate Program on Veterinary Sciences, Universidade Federal do Paraná, Curitiba, Paraná, Brazil; Somali One Health Centre, Abrar University, Somalia; Department of Animal Health and Veterinary Services, Ministry of Livestock, Forestry, and Range, Mogadishu, Somalia.
Ticks and tick-borne diseases
|September 6, 2025
概括
索马里畜牧业的菌暴露率很高,其中50.5%的动物检测呈阳性. 牛的血清活性最高,这表明该地区的Rickettsia africae存在潜在的动物感染风险.
科学领域:
- 兽医微生物学
- 动物传染病
- 公共卫生昆虫学
背景情况:
- 里克特西亚物种是通过传播的阴性,有义务的细胞内细菌,存在动物感染的风险.
- 索马里牲畜和人类的病状况在很大程度上仍然没有特征.
- 雄性是Rickettsia africae的载体,这是一个重要的动物传染病原体.
研究的目的:
- 调查索马里畜牧业里克特西亚物种暴露的血清证据.
- 确定反动物中对Rickettsia africae和Rickettsia rhipicephali的抗体的流行情况.
- 评估Rickettsia spp的潜在动物感染影响. 在研究的地区.
主要方法:
- 在贝纳迪尔和下沙贝尔地区对372只山羊,牛和绵羊的血清样本进行了截面研究.
- 用于检测R. africae和R. rhipicephali的抗体的间接免疫光试验 (IFA).
- 从1:64开始进行两次序列稀释的血清分析.
主要成果:
- 对Rickettsia spp的总体阳性 这一比例为50.5% (188/372),其标位在1: 64至1: 048之间.
- 在21. 0% (78/372) 的患者中检测到R. africae抗体,在10. 2% (38/372) 的患者中检测到R. rhipicephali抗体,在19. 4% (72/372) 的患者中检测到共反应性.
- 牛的血清活性最高 (90.2%),其次是绵羊 (28.6%) 和山羊 (28.4%). 牛和绵羊比山羊有明显的阳性.
结论:
- 这项研究提供了Rickettsia spp的第一个血清证据. 在索马里的反动物中暴露.
- 牛表现出对Rickettsia感染的高度敏感性,这表明它们的作用是人类暴露的潜在哨兵.
- 这些发现强调了对Rickettsia spp的进一步调查的必要性. 索马里的流行和相关的动物感染风险.
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