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Updated: Sep 8, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
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Published on: February 3, 2023

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用蛋白语言模型发现缺失与替代的差异性耐受性

Grant Goldman1, Prathamesh Chati1, Vasilis Ntranos2

  • 1Biological and Medical Informatics Program, University of California, San Francisco, CA, USA; Diabetes Center, University of California, San Francisco, CA, USA.

Cell systems
|September 6, 2025
PubMed
概括

深度突变扫描 (DMS) 实验揭示了基因变化如何影响特征. 这项研究表明氨基酸删除和替代对蛋白质适应性有不同的影响,

关键词:
删除扫描蛋白质语言模型二次结构序列上下文

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