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Updated: Sep 8, 2025

RhoC GTPase Activation Assay
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在结直肠癌中向Cys16的共价抑制剂

Tin-Yan Koo1, Jason Ying Ki Li1, Nga-Sze Lee1

  • 1School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

Cell chemical biology
|September 6, 2025
PubMed
概括

研究人员开发了一种向药物CL16,用于抑制结肠直肠癌中的RhoA (癌症驱动因素). 这种新的方法显示出显著的抗瘤效应,并在临床前模型中促进免疫反应,提供了新的CRC治疗策略.

关键词:
其他基于活动的蛋白质分析抗癌药物化学蛋白质组大肠直肠癌同价抑制剂可定位的氨酸

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