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Updated: Sep 8, 2025

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在TEAD凝聚物中的内源YAP/TAZ分离调节Hippo反应

Tianxin Zhu1, Huan Li2, Siwei Mao3

  • 1Lingang Laboratory, Shanghai 200031, China; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China.

Molecular cell
|September 6, 2025
PubMed
概括

这项研究表明,TEAD凝聚物组织YAP/TAZ信号传递,作为转录激活的枢纽. 了解TEAD凝聚物的动态是开发向治疗的关键.

关键词:
一个 TEAD其他类型YAP/TAZ 公司生物分子凝聚物抑制剂

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