在实验模型中,Sappanone A 是一种潜在的自然PI3K抑制剂,可缓解与代谢功能障碍相关的脂肪肝炎

Xi Qiao1, Qian Li2, Ruiqi Fan2

  • 1Department of Endocrinology, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, China; Department of Pharmacology, School of Basic Medicine, Shanxi Medical University, Taiyuan 030001, China.

Biochemical pharmacology
|September 6, 2025
PubMed
概括

萨帕A可用于治疗与代谢功能障碍相关的脂肪肝炎 (MASH). 这种天然化合物抑制PI3K,减少MASH模型中的肝损伤,炎症和纤维化.

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