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Updated: Sep 8, 2025

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WNT7A/B组建一个GPR124-RECK-LRP5/6共受体复合体,以激活大脑内皮细胞中的β-catenin信号

Robin Heiden1, Laura Hannig1, Calvin J Kuo2

  • 1Institute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany.

The Journal of biological chemistry
|September 6, 2025
PubMed
概括

大脑内皮细胞中的WNT7信号涉及一种新的GPR124-RECK-LRP5/6复合体,独立于FZD受体. 这种独特的途径调节大脑血管生成和血脑屏障的完整性.

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