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Updated: Sep 8, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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长非编码RNA SNHG12通过准E3结合酶TRIM25来定义KEAP1的稳定性和铁性

Yubo Guo1, Shuang Zhu2, Wenjie Wu3

  • 1State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China; Hubei Hongshan Laboratory, Wuhan, Hubei, 430070, China.

The Journal of biological chemistry
|September 6, 2025
PubMed
概括

这项研究确定SNHG12是铁死的一种新型调节剂,这种细胞死亡对癌症治疗至关重要. 通过与TRIM25相互作用,SNHG12的升级促进了铁生,提供了新的治疗点.

关键词:
KEAP1 的使用情况其他类型没有SNHG12一个TIM25铁症

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