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Updated: Sep 8, 2025

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发育规划:产前和产前双A治疗对雌羊肝甲基瘤的影响不同

John Dou1, Soundara Viveka Thangaraj2, Yiran Zhou2

  • 1Department of Epidemiology, University of Michigan, Ann Arbor, USA.

Molecular and cellular endocrinology
|September 6, 2025
PubMed
概括

产前接触过多的或双A (BPA) 显著改变后代的肝脏DNA甲基化. 这些调节新陈代谢的基因表观遗传变化可能会增加晚年代谢疾病的风险.

关键词:
DNA 甲基化双A肝脏产前暴露测试剂

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Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
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