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Updated: Sep 8, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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S100A4 通过驱动多倍体巨型癌细胞芽,促进辐射诱导的瘤重生

Ruyi Zhao1, Yanwei Song2, Jianzhu Xie2

  • 1Department of Vascular Surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai, China.

Cancer letters
|September 6, 2025
PubMed
概括

在放射治疗后,多型巨型癌细胞 (PGCC) 促使结肠直肠癌重生. 向S100A4- ISG15通路可以抑制PGCC的芽,克服治疗耐药性并改善辐射敏感性.

关键词:
脱多化美国政府15干扰剂 I 信号多倍体巨型癌细胞 (PGCC)抗辐射性能在 S100A4瘤重生

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