相关实验视频

Updated: Sep 8, 2025

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

9.6K

类核酸-PEG结合物控制的不匹配敏感DNA杂交

Toshihiko Sakurai1, Yusuke Hamashita2, Takahiro Shibata2

  • 1Department of Biotechnology and Chemistry, Kindai University, Takaya-Umenobe, Higashi-Hiroshima 739-2116 Japan; Graduate School of System Engineering, Kindai University, Takaya-Umenobe, Higashi-Hiroshima 739-2116 Japan.

Analytical biochemistry
|September 6, 2025
PubMed
概括

一种虫类型的PNA-PEG结合物 (i-PPc) 显示出优异的点突变检测. 这种DNA探针只能与互补的DNA形成稳定的双重复合,在生理条件下实现精确的突变诊断.

关键词:
在DNA中虫类型的PNA-PEG结合物启动/关闭类型识别点位变异

更多相关视频

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

1.1K
DNA Tension Probes to Map the Transient Piconewton Receptor Forces by Immune Cells06:53

DNA Tension Probes to Map the Transient Piconewton Receptor Forces by Immune Cells

Published on: March 20, 2021

2.8K

相关概念视频

Mismatch Repair01:20

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
5.2K