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下一代小型分离平台:用于智能分析科学的融合检测,自动化和可持续设计

Erica Alves¹, B M Gurupadayya¹, Prabitha Prabhakaran¹

¹Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysore, India.

Critical reviews in analytical chemistry

|September 7, 2025

概括

微型分离平台正在通过智能自动化设备彻底改变分析科学. 未来的创新重点是人工智能,可持续性和分散诊断的综合系统.

科学领域:

分析科学
微流体学
在芯片上的实验室 (LOC) 技术

背景情况:

微型化正在改变分析科学,
微制造,自动化和数据处理的整合是先进分离平台的关键.

研究的目的:

审查小型分离平台的最新技术进展.
批判性地评估该领域的突破和剩余挑战.
突出适应性分析系统的硬件和智能软件的融合.

主要方法:

关于微注射,预度和检测系统 (UV/Vis,FL,ECD,MS) 的最新文献综合.
分析微控制器,人工智能,物联网和增材制造 (3D打印) 的进展.
检查药物,环境,临床,法医和食品安全领域的应用.

主要成果:

开发具有实时决策能力的自我调节分析设备.
通过3D打印实现LOC系统的快速原型和定制.
在检测灵敏度和系统集成方面取得了重大进展.

结论:

微型分离平台非常有前途,但在流动稳定性,标准化和可靠性方面面临挑战.
未来的系统需要互操作性,能源效率和人工智能引导的分散诊断控制.
下一代的分离科学将将小型化与智能设计和可持续工程结合起来.

关键词:

人工智能集成分析增材制造支持物联网的诊断在芯片上的实验室 (LOC)微型分离平台

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