皮层-皮层唤起的潜能:早期和晚期反应的自动定位和分类
Sahaj A Patel1, Helen Brinyark2, Caila Coyne3
1Department of Electrical and Computer Engineering, University of Alabama at Birmingham, Birmingham, AL, USA.
Journal of neuroscience methods
|September 7, 2025
概括
这项研究引入了一个深度学习框架,可以在皮层-皮层唤起潜力 (CCEPs) 中自动识别N1和N2组件,从而提高大脑网络绘图的准确性. YOLO v10 模型为研究提供了强大的替代手动分析.
科学领域:
- 神经科学是一个神经科学.
- 计算神经科学是一种神经科学.
- 医疗成像医学成像
背景情况:
- 皮质皮质唤起潜能 (CCEPs) 对于使用电刺激绘制大脑网络至关重要.
- CCEP具有早期 (N1) 和晚期 (N2) 组件,反映了直接和间接连接.
- 手动识别CCEP组件是具有挑战性的,因为信号的变化和间隔的差异.
研究的目的:
- 开发一个自动化的深度学习框架,用于本地化和分类CCEP中的N1和N2组件.
- 在CCEP组件识别中克服传统统计方法和手动分析的局限性.
- 为分析患者大脑网络连接提供可靠的工具.
主要方法:
- 使用YOLO v10开发了一个深度学习框架来分析CCEP时代.
- CCEP时代被转换为2D图像,由YOLO模型进行分析.
- 该模型检测和分类N1和N2组件,将图像坐标映射回时间序列数据.
主要成果:
- 该框架在测试数据集上的IoU值为0.5时,实现了0.928的平均平均精度 (mAP).
- 对9名耐药性患者的内EEG数据进行了验证.
- 在两个机构的15名额外患者中,在超过4000个时代上证实了通用性.
结论:
- 拟议的深度学习框架准确地检测和分类CCEP组件 (N1和N2).
- 这种自动化方法为手动CCEP分析提供了强大而可靠的替代方案.
- 该方法在推进脑网络研究和的临床解释方面具有重大潜力.
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