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Updated: Jan 18, 2026

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
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Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation

Published on: December 15, 2017

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双功能的fab-scFv融合抗体通过准hFcRn介导的结肠丰富和TNF-α中和来缓解性结肠炎

Miao He1, Li Li2, Guorong Jiang2

  • 1School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, PR China; School of Pharmacy, Dali University, Dali, 671000, Yunnan, PR China; Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, School of Pharmacy, Dali University, Dali, Yunnan, PR China.

International journal of biological macromolecules
|September 7, 2025
PubMed
概括

一种新型的融合蛋白,IFX-F8,增强了针对性结肠炎 (UC) 治疗的抗TNF-α疗法的输送到肠道. 这种工程蛋白针对人类新生儿的Fc受体 (hFcRn) 以改善与标准治疗相比的肠道保留和疗效.

关键词:
抗瘤亡因子-α 的抗瘤亡因子.双特异性抗体 双特异性抗体人类新生儿Fc受体有针对性的治疗.性结肠炎是一种

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