在复杂的大动脉内移植中,手术时间和术后结果之间的关联:单个中心的回顾性观察研究
Federico F Pennetta1, Thomas Le Houérou1, Mickael Palmier1
1Vascular Surgery, Aortic Centre, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, INSERM UMR_S 999, Université Paris Saclay, Paris, France.
概括
在复杂的内血管大动脉修复中,延长的操作时间 (OT) 与更高的30天死亡率有关. 在研究期间,操作时间减少,显示了学习曲线效应和改善的结果.
科学领域:
- 血管外科 血管外科
- 血管内修复 血管内修复
- 外科手术的结果
背景情况:
- 复杂的内血管大动脉修复 (EVAR) 包括窗口 (FEVAR),分支 (BEVAR) 和弧形分支 (aBEVAR) 的程序.
- 操作时间 (OT) 是手术过程中的关键指标,可能会影响患者的治疗结果.
- 了解影响OT的因素对于优化复杂的EVAR程序至关重要.
研究的目的:
- 在复杂的EVAR中评估操作时间 (OT) 和30天术后结果之间的关联.
- 确定导致OT变化的因素,包括医院体积和学习曲线.
- 评估长期OT对并发症和死亡率的影响.
主要方法:
- 对530名接受复杂EVAR (FEVAR,BEVAR,aBEVAR) 的患者进行了回顾性观察队列研究.
- 运行时间定义为从第一次动脉接入到关闭的间隔.
- 分析包括诸如医院体积,学习曲线,辅助程序和技术等因素,以及30天的结果.
主要成果:
- 平均OT因手术类型而异 (FEVAR: 145 分钟,BEVAR: 181 分钟,aBEVAR: 159.5 分钟).
- 在最长的OT tertile (9.1%) 与最短的 (0.0%) 相比,三十天死亡率显著更高 (p < .001).
- 多变量分析证实长时间的OT作为30天死亡率增加的独立预测因子 (aOR为每分钟1.010).
- 在研究期间,OT下降,表明学习曲线效应 (p < .001).
结论:
- 经过复杂的EVAR后,长时间的操作时间独立地与30天死亡率的增加有关.
- 随着时间的推移,随着OT的减少,结果有所改善,这表明了显著的学习曲线效应.
- 这项单中心研究的结果强调了在复杂的大动脉修复中优化OT的重要性,尽管由于回顾性设计,建议谨慎使用.
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