Cannabinoids 对 情绪状态 和 代表性 不足 的 群体 中 的 酒精 使用 的 影响: 通过 感知 歧视 的 适度
Renée Martin-Willett1, Carillon J Skrzynski1, Angela D Bryan1
1Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado, USA.
Human psychopharmacology
|September 8, 2025
概括
大麻素 (CBD) 可能会减少负面情绪,而四大麻素 (THC) 则没有显著的影响. 感知到的歧视影响了这些结果,但大麻类型都没有影响饮酒行为.
科学领域:
- 心理药理学 心理药理学
- 大麻研究 大麻研究
- 在健康方面存在差异.
背景情况:
- 有限的研究存在于THC和CBD等特定大麻素对情绪和行为的影响.
- 在研究中代表性不足的人群经常面临独特的压力因素,例如被认为是歧视,这可能会影响治疗结果.
- 了解这些因素对于开发有效和公平的基于大麻的干预措施至关重要.
研究的目的:
- 调查四大麻素 (THC) 和大麻素 (CBD) 对负面情绪和酒精消费的影响.
- 为了确定所感知的歧视是否会缓和THC和CBD对情绪和饮酒行为的影响.
- 对来自代表不足的种族,种族,性别或性认同群体的个体检查这些影响.
主要方法:
- 一项随机对照试验涉及172名参与者,分为非大麻使用者,THC使用者和CBD使用者.
- 参与者在基线,2周和4周被评估为情绪 (抑郁焦虑压力表) 和饮酒行为 (饮酒日数).
- 使用感知歧视量表 (PDS) 来分析调节效应来衡量感知歧视.
主要成果:
- 与使用THC的人相比,使用CBD的参与者在研究期间表现出更大的负面情绪症状减少.
- 当排除非使用者时,观察到大麻状况,时间和感知歧视之间的显著相互作用,这表明THC和CBD用户的平均和高PDS水平的情绪改善.
- 没有发现THC或CBD对与酒精有关的结局有显著影响.
结论:
- 大麻 (CBD) 显示出短期减少负面情绪症状的潜力.
- 感知到的歧视显著影响了大麻素使用和情绪调节之间的关系.
- 在这一群体中,THC和CBD的使用都与酒精使用障碍的风险增加无关.
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