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基于活动的ubiquitin探针捕获了deubiquitinases的硫化状态

Zian Chen1, Guorui Li2, Jiahao Zhang1

  • 1State Key Laboratory of Chemo and Biosensing, School of Biomedical Sciences, Hunan University, Changsha, 410082, China.

Angewandte Chemie (International ed. in English)
|September 8, 2025
PubMed
概括

研究人员开发了基于全方位的新型活性探针 (Ub-ABPs),专门捕获氧化二基酶 (DUB-SOH). 这些探针有助于了解氧化应激如何影响癌症等疾病中的DUB功能.

关键词:
基于活动的ubiquitin探测器杜比奎廷酶的使用方法后翻译修改后的修改.减少氧化物的信号传输.硫化 硫化

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