在越南的四个地区医院实施抗微生物管理计划的可行性
Jaslyn Doshi1, Yen Ngoc Pham2, Thuy Thu Ma2
1Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Journal of infection and public health
|September 8, 2025
概括
越南的抗菌药物管理计划减少了抗菌药物的使用和死亡率,但没有改善处方的适当性. 需要进一步努力打击抗微生物药物耐药性.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 公共卫生政策 公共卫生政策
背景情况:
- 抗微生物药物耐药性 (AMR) 是由于过度和不当使用抗微生物药物导致的.
- 抗微生物药物管理 (AMS) 计划促进了明智的抗微生物药物处方.
- 这项研究评估了越南地区医院的AMS可行性和有效性.
研究的目的:
- 评估越南地区医院的AMS计划的实施情况.
- 确定AMS计划对抗微生物消费和处方适当性的影响.
- 评估抗微生物成本和全因死亡率的变化.
主要方法:
- 在四个越南地区医院进行了为期6个月的前后研究.
- 干预措施包括建立AMS委员会,分发指南,培训工作人员,并进行反审计.
- 共同初级结果:每月消费的抗微生物药物和处方的适当性;二级结果:成本和死亡率.
主要成果:
- 在高度的利益相关方参与下,AMS计划得到了成功实施.
- 不适当的处方率仍然很高 (基线为79.0%,干预后为80.3%).
- 观察到抗菌药物消费量略有减少 (4.2 DDD/100个睡日/月) 和所有原因死亡率 (RR=0.32).
结论:
- 在越南的地区医院,AMS干预是可行的,减少了消费和死亡率.
- 持续高的不适当的处方率需要加强管理工作.
- 加强AMS至关重要,以解决地区一级的AMR驱动因素.
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