以睡眠为导向的非药物干预措施在预防妄想的效果:对随机对照试验的系统审查
Ezgi Mutluay Yayla1, Emine Kaplan Serin
1Ezgi Mutluay Yayla, Health Sciences Faculty, Tarsus University, 33400 Mersin, Turkey, ezgiyayla@tarsus.edu.tr.
Croatian medical journal
|September 8, 2025
概括
耳塞和口罩等睡眠干预措施在重症监护室 (ICU) 预防妄想方面显示出混合的结果. 虽然一些研究发现了益处,但另一些则没有,这表明在预防狂妄症的有效性方面存在差异.
科学领域:
- 关键护理医学 关键护理医学
- 睡眠科学 睡眠科学
- 基于证据的实践.
背景情况:
- 痴呆症是重症监护室 (ICU) 中常见且严重的并发症.
- 目前正在探索针对睡眠障碍的非药物干预措施,以预防妄想.
- 需要标准化的干预措施来改善重症监护机构患者的治疗结果.
研究的目的:
- 系统地审查对睡眠导向的非药物干预措施的随机对照试验 (RCT),以预防ICU中的妄想.
- 评估这些干预措施的有效性和安全性.
- 综合当前关于它们对妄发病率和睡眠质量影响的证据.
主要方法:
- 在主要数据库 (PubMed, Web of Science, Scopus, Cochrane Library) 中对2019-2024年间发表的RCT进行全面的文献搜索.
- 包括英语研究,重点研究以睡眠为导向的,非药物干预措施,以预防ICU中的妄想.
- 两位独立研究人员使用Joanna Briggs Institute工具进行方法质量评估.
主要成果:
- 包括8个RCT,共649名参与者.
- 六项研究评估了耳塞和口罩;三项研究显示在预防狂妄症方面具有有效性,而三项研究发现没有显著效果.
- 一项使用耳塞和口罩捆绑的研究报告了积极的结果;四项研究表明对睡眠有影响. 没有报告任何不良事件.
结论:
- 以睡眠为导向的干预措施,包括耳塞和眼罩,在预防ICU中的妄想方面具有可变的有效性.
- 虽然一些高质量的研究表明妄发病率显著降低,但另一些研究报告没有效果,这强调了需要进一步研究的必要性.
- 这些发现强调了需要了解导致妄预防策略结果变化的因素.
相关概念视频
01:13Insufficient Sleep and Sleep Deprivation
840
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
840
01:19Management of Insomnia
543
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
543
01:17Sedatives and Hypnotics Drugs: Miscellaneous Agents
519
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
519
01:24Substance Use Disorders Affecting Sleep
403
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
403
01:23Sedatives and Hypnotics: Overview
1.4K
Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics.
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
1.4K
02:07Blind Procedures
13.0K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.0K