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Updated: Jan 18, 2026

Author Spotlight: Generating Neuronal Phenotypic Profiles - A Protocol to Culture and Image Human Midbrain Dopaminergic Neurons
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在人类中使用渐变树增强中枢神经系统 (CNS) 小分子的半衰期预测

Hong Wang1, Pan Zhang1, Stephen J Barigye1

  • 1Computational Science & Artificial Intelligence, Xenon Pharmaceuticals Inc, Burnaby, BC, Canada.

Future medicinal chemistry
|September 8, 2025
PubMed
概括

一个机器学习模型准确地预测了开发早期中枢神经系统 (CNS) 药物的人类半衰期. 该工具有助于优先考虑候选药物,并利用精心策划的数据集来改进未来的预测.

关键词:
中枢神经系统的小分子.人类半衰期 人类半衰期发现药物的发现.渐变树增强了渐变树的增强.机器学习是机器学习.

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