老年人营养风险指数和胸前大动脉形态变化之间的关联在癌症中成年人接受了对比计算断层扫描
Zhijie Jian1, Zixuan Meng2, Xiangrui Qiao2
1Department of Medical Imaging, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Frontiers in nutrition
|September 8, 2025
概括
癌症患者的营养不良与大动脉直径和曲度的增加有关. 这突显了营养不良作为心血管疾病在心脏瘤学中的潜在风险标志物.
科学领域:
- 心脏瘤学 - 心脏瘤学
- 血管健康 血管健康
- 营养科学 营养科学
背景情况:
- 癌症幸存者面临心血管疾病 (CVD) 的风险增加,部分原因是营养不良.
- 营养不良与不良的心血管结果有关,大动脉形态变化影响血管血动力学.
- 癌症患者的营养不良和大动脉形态之间的关系尚未得到充分证实.
研究的目的:
- 研究成年癌症患者的营养不良和胸前大动脉形态变化之间的关联.
- 探索营养不良作为心脏瘤学中的潜在风险标志物.
主要方法:
- 这是一项涉及189名没有先前心血管疾病的成年癌症患者的横截面研究.
- 患者根据老年营养风险指数 (GNRI) 进行分类:中度至严重 (<92),低 (92-98),无风险 (≥98).
- 胸前动脉形态,包括细分直径和扭曲度,使用计算机断层扫描 (CT) 扫描进行了评估.
主要成果:
- 一半的患者有营养不良的风险.
- 营养不良风险 (较低的GNRI) 与较大的大动脉直径和上升大动脉,大动脉,胸前大动脉和下降胸前大动脉的形性增加有显著关联.
- 在GNRI值与大动脉直径和扭曲度之间发现了负线性关联.
结论:
- 由GNRI评估的营养不良与癌症患者的大动脉重塑 (直径和形) 有关.
- 这表明营养不良可能成为心脏瘤学中的新风险标志物.
- 进一步的研究应该检查营养支持是否可以改善GNRI并减轻大动脉变化.
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