在接受手术的患者中使用处理心脏声音信号的不显眼的连续血液动力学监测方法:概念验证研究
Woo-Young Seo1, Sang-Wook Lee2, Yong-Seok Park2
1Biomedical Engineering Research Center, Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea.
Biomedical engineering letters
|September 8, 2025
概括
心脏声音指数与肝移植期间的血液动力学参数相关. 这表明心脏声音在复杂的手术中提供了最少的侵入性监测.
科学领域:
- 心脏病学 心脏病学
- 麻醉学 麻醉学
- 生物医学工程 生物医学工程
背景情况:
- 心脏声音提供了对心脏功能的洞察力,但在血液动力学监测中未得到充分利用.
- 在肝移植等复杂手术中,对血液动力学进行最少的侵入性监测至关重要.
研究的目的:
- 为了研究肝移植手术期间心脏声音指数和血液动力学参数之间的关系.
- 为了评估心脏声音的潜力,实时进行微创血动力学监测.
主要方法:
- 分析了五个手术阶段80名肝移植患者的数据.
- 与血液动力学参数 (平均血压,SV,SVR,SVV) 进行心脏声音指数比较 (S1/S2振幅,缩时间间隔,STV).
- 使用皮尔森相关性,布兰德-阿尔特曼分析和CCC来评估关系.
主要成果:
- 在心脏声音指数和血液动力学参数之间发现了显著的相关性.
- STV显示了与中风体积变化 (SVV) 的最强相关性 (r=0.687-0.721).
- 分别与dP/dt_max和SVR相关的S1和S2振幅.
结论:
- 心脏声音参数,包括STV,S1和S2振幅,可以反映肝移植期间的血液动力学变化.
- 这些发现支持使用心脏声音分析作为在复杂的手术环境中进行微创血动力学监测的有价值工具.
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