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产后体重增加率对早产婴儿严重视网膜病变的预测价值:回顾性分析

Jiangya Wang¹, Qingmin Ma², Fangfang Du¹

¹Department of Pediatrics, Hebei General Hospital, Shijiazhuang, 050000, People's Republic of China.

Journal of multidisciplinary healthcare

|September 8, 2025

概括

较低的产后体重增加率 (WGR) 是早产婴儿早产视网膜病变 (ROP) 的重要危险因素. 每天WGR低于18g可能预测严重的ROP,有助于早期干预.

科学领域:

新生儿眼科新生儿眼科
产周医学产周医学
儿科重症监护儿科重症监护

背景情况:

在中国,早产视网膜病变 (ROP) 的发病率正在增加.
目前的ROP查方法 (妊娠年龄,出生体重) 有局限性.
产后体重增加率 (WGR) 显示出作为ROP的预测标志物的潜力.

研究的目的:

调查早产婴儿ROP发病率的危险因素.
评估WGR对ROP的预测值,尤其是严重的ROP.
在中国人群中建立ROP预测的WGR值.

主要方法:

对230名早产婴儿 (GA ≤32周,BW ≤2000g) 的回顾性队列研究.
分析临床数据,包括妊娠年龄 (GA),出生体重 (BW) 和WGR.
多变量物流回归和ROC曲线分析以确定风险因素和预测值.

主要成果:

较低的GA,BW和WGR是ROP的独立风险因素.
WGR <24.5g/天预测了任何具有高灵敏度和特异性的ROP (AUC=0.939).
WGR <18 g/天预测严重的ROP,具有100%的灵敏度 (AUC=0.865).

结论:

降低GA,BW和WGR增加了ROP的敏感性.
缓慢的WGR是严重ROP风险的关键指标.
WGR值可以帮助早期检测和管理ROP.

关键词:

出生的体重出生时的体重.怀孕年龄怀孕年龄过早生育的视网膜病变有关风险因素的风险因素.体重增长率的增长率是什么

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