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针对细胞的PD-1激动剂是强大的NK细胞抑制剂

Harriet C Pope1,2, Ana L Chiodetti1, Alice Newey1

  • 1Immunocore Ltd., Abingdon, United Kingdom.

Frontiers in immunology
|September 8, 2025
PubMed
概括

一种针对胰腺β细胞的PD-1 (编程细胞死亡蛋白1) 激动剂的新型双特异性分子抑制了NK细胞的活动,为自身免疫性疾病提供了潜在的治疗方法.

关键词:
在 NK 细胞中, NK 细胞是最重要的.抑制NK细胞的抑制.在PD-1路径上.自身免疫性疾病 自身免疫性疾病针对细胞的PD-1激动剂.第1类糖尿病 1型糖尿病

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