在产前检查期间进行机会性宫癌查:迈向早期检测的一小步
Ruchi Verma1, Ritu Sharma1, Pinky Mishra1
1Obstetrics and Gynaecology, Government Institute of Medical Sciences, Greater Noida, IND.
Cureus
|September 8, 2025
概括
怀孕和非怀孕妇女的宫癌查显示,细胞学异常和人类乳头瘤病毒 (HPV) 阳性率相似. 使用HPV DNA测试或细胞学进行产前查是可行的,并建议这样做.
科学领域:
- 妇科 妇科医生 妇科
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 宫癌是印度的主要公共卫生问题.
- 早期检测和查对于治疗宫癌至关重要.
- 怀孕和非怀孕妇女之间的查结果的比较可以为公共卫生战略提供信息.
研究的目的:
- 为了比较孕妇和非孕妇之间的细胞学异常和人类乳头瘤病毒 (HPV) 阳性率.
- 评估子宫癌查在产前期间的可行性.
主要方法:
- 在北印度的第三级护理中心进行前性观察研究.
- 120名妇女 (60名孕妇,60名非孕妇) 接受了传统的巴普查和联合测试 (基于液体的细胞学和HPV DNA测试).
- 用贝塞斯达系统解释了涂抹;结果在各组之间进行了比较.
主要成果:
- 超过93%的参与者获得了令人满意的宫涂抹结果.
- 在孕妇和非孕妇组中都检测到先发性病变 (ASC-US,LSIL).
- 在孕妇和非孕妇之间,HPV DNA阳性率是可比的.
结论:
- 细胞学异常和HPVDNA阳性的患病率在孕妇和非孕妇中是相似的.
- 使用HPV DNA测试或细胞学进行宫癌查可以有效地整合到产前护理中.
- 增加产前检查支持对子宫癌进行机会性查.
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