阻塞性睡眠呼吸暂停在异常性内高血压:系统性审查和元分析
Mohammad Karam1,2, Abdulmalik Alsaif3,4, Dalal Alroumi2
1Department of Ophthalmology and Visual Sciences, McGill University Health Center, Montreal, Canada.
Neuro-ophthalmology (Aeolus Press)
|September 8, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 与异常性内高血压 (IIH) 有显著的关联. 近42%的IIH患者患有OSA,因此需要对这种常见的睡眠障碍进行查.
科学领域:
- 神经学 神经学
- 肺部病理学 肺部病理学
- 眼科医生 眼科 眼科
背景情况:
- 异常性内高血压 (Idiopathic intracranial hypertension,IIH) 是一种神经疾病,其特征是没有明确原因的内压力增加.
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的与睡眠有关的呼吸障碍,具有潜在的全身健康影响.
- 需要进一步调查OSA和IIH之间的关系,以告知临床实践.
研究的目的:
- 系统地审查和分析关于阻塞性睡眠呼吸暂停 (OSA) 与异常性脑内高血压 (IIH) 之间的关联的现有文献.
- 确定在被诊断为IIH的患者中OSA的综合患病率.
主要方法:
- 按照PRISMA指南进行了系统审查和元分析.
- 在MEDLINE,EMBASE和Cochrane图书馆的数据库中进行了搜索.
- 八项涉及241名患者的研究被纳入最终分析.
主要成果:
- 在IIH患者中,OSA的整体综合患病率为42.4% (95% CI:0.258至0.609),表明存在显著的关联 (p < .05).
- 亚组分析显示,确认OSA诊断的患病率为40.7%,阳性OSA查的患病率为46.4%.
- 研究结果表明,这两种情况之间存在强有力的联系.
结论:
- 很大一部分新诊断IIH的患者也患有OSA.
- 临床医生应考虑对IIH患者进行OSA查,以促进及时诊断和管理.
- 进一步的研究可能会探索将OSA和IIH联系在一起的病理生理机制.
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