母亲添加β-胡卜素对后代小的肠道健康有长期影响
Taiping Wang1,2, Da Wan1,2, Tianyu Ren1
1College of Animal Science and Technology, College of Veterinary Medicine, Jilin Agricultural University, Changchun, Jilin, China.
Frontiers in microbiology
|September 8, 2025
概括
母亲补充β-胡卜素改善了的肠道健康状况,改变了肠道微生物群,显示出化后长达42天的持久益处. 这种饮食策略增强了小的高度和屏障功能,这表明家禽养殖是一个有前途的方法.
科学领域:
- 禽类营养和肠道健康
- 动物微生物学动物微生物学
- 生殖营养 生殖营养
背景情况:
- 富含β-胡卜素的孕产妇饮食可以增强胚胎发育和后代肠道微生物群.
- 然而,母性β-胡卜素对化后小肠道健康的长期影响需要进一步研究.
研究的目的:
- 研究母体食β-胡卜素补充剂对化后小肠发育和微生物群落的影响.
- 评估母体β-胡卜素对子肠道健康和生长性能的持续影响.
主要方法:
- 在6周的时间里,母被食了具有不同β-胡卜素含量 (0,120或240毫克/公斤) 的饮食.
- 卵被化,结果的小在化后的6周内以标准饮食养.
- 肠道形态,基因表达和乳腺微生物群在42天后被分析.
主要成果:
- 来自补充组的小显示了增强的小高度,小高度与密室深度的比率,以及杯状细胞密度.
- 母亲的β-胡卜素增加了肠道屏障基因 (MUC2,ZO1,ZO2) 的表达.
- 观察到明显的乳腺微生物群落,特定的细菌与改善的肠道参数正相关.
结论:
- 孕产妇补充β-胡卜素可以为后代的肠道健康带来持续的好处.
- 这些好处可能通过调节肠道微生物组来调节.
- 这突显了β-胡卜素是改善家禽肠道健康的关键营养素,从生命早期开始.
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