在左侧乳腺癌治疗中,自由呼吸和深呼吸之间的比较 呼吸保持在左侧乳腺癌治疗中
Hideharu Miura1,2, Yoshiko Doi3, Soichiro Ishihara1
1Hiroshima High-Precision Radiotherapy Cancer Center, Hiroshima, Japan.
概括
与自由呼吸 (FB) 相比,深深吸入呼吸 (DIBH) 对左侧乳腺癌患者显著降低了心脏辐射剂量. 虽然DIBH降低了相对照射的肺体积,但它增加了绝对照射的肺体积.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
背景情况:
- 左侧乳腺癌的治疗需要仔细规划,以尽量减少对有风险的器官的辐射暴露.
- 心脏和左肺在左侧乳腺癌放射治疗中特别容易受到辐射诱导的毒性.
研究的目的:
- 为了比较深呼吸呼吸 (DIBH) 与自由呼吸 (FB) 治疗计划的疗效.
- 评估DIBH对左侧乳腺癌患者向心脏和左侧肺部输送的辐射剂量的影响.
主要方法:
- 55名患有左侧乳腺癌的患者进行了3D合规放射治疗的回顾性比较.
- 对心脏和左肺的辐射剂量分析,用于FB和DIBH治疗计划.
- 处方剂量为42.56 Gy,分为16个部分.
主要成果:
- 与FB相比,DIBH将心脏平均剂量降低了55% (2.0 Gy与0.9 Gy相比,p < 0.001).
- DIBH显著增加了左肺体积 (980.5厘米对1713.0厘米,p < 0.001).
- DIBH降低了相对照射的左肺体积 (V20Gy:11.7%与10.1%,p < 0.001),但增加了绝对照射的左肺体积 (V20Gy:118.2cc与172.5cc,p < 0.001).
结论:
- 深呼吸喘息 (DIBH) 是治疗左侧乳腺癌的一种有效的放射治疗技术.
- DIBH显著降低了心脏辐射剂量和相对照射的左肺体积.
- 绝对照射的肺体积增加了DIBH,需要仔细考虑.
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