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合成CT的质量评估使用马分析前列腺癌MR-only放射治疗

Viktor Babka¹, Lubos Rehounek², Iva Jakubcova³

¹Department of Oncology and Radiotherapy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

|September 8, 2025

概括

一个新的软件工具MRGamma验证了合成CT图像用于前列腺癌的MR-only放射治疗. 这种方法确保了图像质量,支持无需传统CT扫描的放射治疗计划.

科学领域:

医学物理医学物理
放射治疗技术放射治疗技术
图像分析图像分析

背景情况:

评估合成CT (sCT) 图像质量对于前列腺癌中仅用MR进行放射治疗至关重要.
挑战包括缺乏电子密度信息和MRI和PCT之间的注册不确定性.

研究的目的:

通过使用马分析,评估用于仅MR前列腺癌放射治疗的sCT图像的质量.
为此评估引入和验证一个软件工具MRGamma.

主要方法:

开发了一个MATLAB应用程序MRGamma,用于Hounsfield单位 (HU) 不一致的2D和3D马分析 (GA).
使用MRCAT算法进行sCT生成,并应用GA,其值为100 HU/70 HU和3 mm DTA.
通过注册,重新采样和裁剪来标准化图像尺寸.

主要成果:

MRGamma显示了sCT和CT图像之间的高度一致.
对于3D GA (100 HU,3 mm),95.5%的voxel通过了,这表明图像质量很好.
在组织接口和空气腔中发现了差异;平均玛值很低.

结论:

该MRGamma应用程序有效评估sCT质量,确认MR-only放射治疗的可行性.
该工具支持基于MR的治疗计划,可能降低成本和辐射暴露.
实施可以提高临床工作流程效率和患者安全.

关键词:

只有MR的工作流.仅使用MRI的治疗计划前列腺癌放射疗法前列腺癌放射治疗

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