用银纳米粒子增强的生物陶密封剂的物理化学和抗菌性质:一个体外评估
Karam Ahmed1,2, Nik Rozainah Nik Abdul Ghani1, Okba Mahmoud3,4
1Conservatives Unit, School of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, 16150, Malaysia.
Clinical, cosmetic and investigational dentistry
|September 8, 2025
概括
将银纳米颗粒添加到生物陶密封剂中可以增强抗菌活性和转化程度. 较高的纳米颗粒度提高了抗菌性质,但降低了透深度到侧面通道.
科学领域:
- 牙科材料科学 牙科材料科学
- 纳米技术在牙周内科中的应用.
背景情况:
- 生物陶密封剂在内牙治疗中至关重要.
- 增强密封剂的特性,如抗菌疗效和转化,是正在进行的研究领域.
研究的目的:
- 研究不同度的银纳米颗粒对生物陶密封剂性能的影响.
- 分析转化度 (DC) 与抗菌功效之间的相关性.
- 评估对横向通道透深度的影响.
主要方法:
- AH Plus生物陶密封剂被修改为2.5%,5%和10%的银纳米粒子 (AgNPs).
- 针对Enterococcus faecalis的抗菌疗效使用随时间的直接接触测试 (DCT) 进行了测试.
- 使用FTIR测量转换程度,通过X射线检查评估透深度.
主要成果:
- 抗菌活性和转化程度随着AgNP度的增加而增加.
- 在DC和抗微生物活性之间观察到强烈的正相关性.
- 增加的AgNP度导致横向通道的透深度降低.
结论:
- 10%的AgNP度显示出抗菌活性和DC的最显著增强.
- 较高的AgNP度对密封物透到侧面通道产生了负面影响.
- 银纳米颗粒显示出改善生物陶密封器性能的希望.
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