一个跨学科的实践基因组学课程,适用于高中到本科教育
Sophie Zaaijer1,2, Simon C Groen1
1University of California Riverside, Riverside, California, USA.
Journal of microbiology & biology education
|September 8, 2025
概括
本课程向高中生介绍基因组学概念,使用发酵和DNA测序. 它增强了科学素养,为一个由基因组学驱动的世界准备了多样化的学习者.
科学领域:
- 基因组学教育 基因组学教育
- 分子生物学分子生物学
- 生物信息学是一种生物信息学.
背景情况:
- 基因组知识对于医疗保健,流行病和生物技术至关重要.
- 基因组学教育在中学教育中是有限的.
- 需要实践课程来教授基因组学概念.
研究的目的:
- 为高中和早期本科生 (14-21岁) 提供模块化,实践性的课程.
- 通过发酵实验引入关键的基因组学概念.
- 培养观察,实验设计和定量推理方面的技能.
主要方法:
- 学生探索DNA,微生物继承,并分析真实DNA测序数据.
- 该课程整合了分子生物学,生物信息学和数据分析.
- 便携式纳米孔测序技术 (Oxford Nanopore MinION) 提供了真实的数据集.
主要成果:
- 学生从事一个完整的科学过程,从探索到正式的报告写作.
- 微生物物种识别等活动可以提高分析能力.
- 该课程与下一代科学标准 (NGSS) 和愿景和变革 (V&C) 框架保持一致.
结论:
- 这种课程使得分子生物学对各种学习者来说是可访问和可联系的.
- 它为学生提供了必要的工具,以在基因组学驱动的世界中有意义地参与.
- 该计划支持跨学科的学习,并提高整体的科学素养.
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