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Updated: Jan 18, 2026

A High-content Assay for Monitoring AMPA Receptor Trafficking
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A High-content Assay for Monitoring AMPA Receptor Trafficking

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PI(3) P协调SNX17和SNX27依赖的蛋白质循环,以实现长期的突触可塑性

Pilar Rivero-Ríos1,2, Tunahan Uygun1,2, Garrett D Chavis3,4,5

  • 1Life Sciences Institute, University of Michigan , Ann Arbor, MI, USA.

The Journal of cell biology
|September 8, 2025
PubMed
概括

动态酸-3-酸盐 (PI(3) P) 合成驱动蛋白质循环通路,SNX17-Retriever和SNX27-Retromer,对于突触可塑性和长期强化 (LTP) 是必不可少的. 这种脂质信号传递对于脊柱结构变化和突触中的蛋白质循环至关重要.

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