[扩散层状角膜炎:零星和集群形式]
V M Sheludchenko1,2, Yu Yusef1, N V Sheludchenko1
1Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Vestnik oftalmologii
|September 8, 2025
概括
在LASIK手术后的扩散性叶片状角膜炎 (DLK) 发生在零星和集群形式. 识别和消除有毒的外科药物和改善片管理可以预防这种并发症.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 激光视力校正 激光视力校正
背景情况:
- 扩散叶状角膜炎 (DLK) 是叶状角膜外科手术后的一种已知的并发症.
- DLK存在两种不同的临床形式:零星和集群,两者都受到外科手术因素的显著影响.
研究的目的:
- 为了调查不同扩散的状角质炎变体的发病率.
- 确定导致DLK的特定外科手术触发因素.
- 概述DLK的区分特征和有效的预防策略.
主要方法:
- 分析了来自19783名年龄在18-45岁的患者的数据,这些患者接受了激光辅助在位瘤修复 (LASIK).
- 患者队列包括97%的近视和3%的近视纠正病例.
- 评估与DLK相关的临床形式,手术原因和患者结局.
主要成果:
- 零星DLK的发生率为1:110,而集群形式的发生率更高,为1:20.
- 集群形式的DLK主要与眼卫生,角质瘤和手套中的有毒物质有关;消除这些因素阻止了进展.
- 零星的DLK与影响树皮界面的短暂触发器相关;在高视眼 LASIK 患者中没有观察到DLK.
结论:
- 在LASIK过程中DLK的主要手术触发因素包括因片重新定位问题而引起的树叶界面不稳定性,平面除特征和手术期间对有毒物质的暴露.
- 针对特定的外科手术元素可以减轻扩散叶状角膜炎的风险和进展.
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