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Updated: Jun 29, 2026

Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment
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Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment

Published on: June 28, 2018

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一种最小侵入性的方法,用于生成肺癌的同基因正位素小鼠模型

Danielle J Foster1, Sunny C Huang2, Jennifer A Petsche3

  • 1Stead Family Department of Pediatrics, University of Iowa Health Care; Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa.

Journal of visualized experiments : JoVE
|September 8, 2025
PubMed
概括

研究人员开发了一种新的手术方法,在小鼠中诱导非小细胞肺癌 (NSCLC). 这种技术可以监测瘤生长,并在相关的临床前模型中测试新的癌症疗法.

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相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...