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通过响应表面方法和微生物反应器查优化再生微型胰岛素的生产

Esra Ayan1,2,3, Ali Özhan Aytekin4, Ahmet Kati2,3

  • 1Department of Molecular Biology and Genetics, Faculty of Science, Koç University, Istanbul, Türkiye.

PloS one
|September 8, 2025
PubMed
概括

通过混合微尺度和统计建模方法进行工程化微型胰岛素 (nMPI) 生产. 优化的生物处理实现了高产量,证明了E. coli重组蛋白表达的可扩展平台.

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