怀孕期间的水感染,孕产妇和胎儿的结果:系统性审查
Jose Camones-Huerta1, Alexander Cordero-Campos1, Alheli Cuya-Sahua1
1School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
Journal of infection in developing countries
|September 8, 2025
概括
孕妇中Mopox感染对胎儿发育构成风险,包括流产和死产. 更多的研究对于有效地理解和管理这些不良的周产期结果至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 麻疹 (mpox) 是一种新兴的传染病,全球发病率不断增加.
- 关于其对怀孕和围产期结果的影响的证据有限,特别是在资源较低的环境中.
研究的目的:
- 系统地综合当前关于怀孕期间与mopox感染相关的孕产妇和胎儿结果的证据.
主要方法:
- 按照PRISMA指南进行了系统审查,搜索了PubMed,Scopus,科学网络和Embase.
- 包括的研究包括案例报告,案例系列,队列和观察设计.
- 由于异质性和小样本大小,对6项符合条件的研究 (共471项) 进行了描述性分析.
主要成果:
- 在6项研究中,包括33名18-29岁的孕妇;mopox在32例病例中得到PCR确认.
- 临床症状包括皮疹,生殖器损伤和全身症状. 没有报告任何产妇死亡.
- 不良的胎儿结果包括流产 (9.1%),死产 (6.1%),以及4例子宫内死亡;84.8%的怀孕导致活产. 发病后出现的并发症包括橄水和垂直传播.
结论:
- 怀孕期间的Mopox感染与出现不良周产期结局的显著风险有关.
- 目前的证据有限,这凸显了迫切需要更可靠的数据.
- 调查结果强调,需要更新关于怀孕期间mpox的临床和公共卫生指南.
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