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Updated: Jan 18, 2026

Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
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Published on: October 17, 2018

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通过寨卡病毒激活PD-1/PD-L1免疫检查点

Chenxi Wang1, Yubin Xie2, Weixin Li1

  • 1School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.

PLoS pathogens
|September 8, 2025
PubMed
概括

寨卡病毒 (ZIKV) 激活了PD-1/PD-L1免疫检查点. 通过抗PD-L1抗体阻断这种途径,可以降低病毒载荷并增强抗ZIKVT细胞反应,这表明一种潜在的抗病毒策略.

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