Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

7.0K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
7.0K
Association Areas of the Cortex01:21

Association Areas of the Cortex

8.9K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
8.9K
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

2.3K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
2.3K
Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

3.9K
The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...
3.9K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.1K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.1K
Indirect Motor Pathways01:22

Indirect Motor Pathways

3.0K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
3.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Beyond Drug Reward: Heritable Sensitivity to Cocaine Aversion as a Determinant of Addiction Vulnerability.

eNeuro·2026
Same author

Persistent vulnerability to heroin relapse after more than one year of abstinence in rats.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Author Correction: A µ-opioid receptor superagonist analgesic with minimal adverse effects.

Nature·2026
Same author

Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex.

eLife·2026
Same author

A µ-opioid receptor superagonist analgesic with minimal adverse effects.

Nature·2026
Same author

Persistent vulnerability to heroin relapse across the adult lifespan in rats.

bioRxiv : the preprint server for biology·2026
Same journal

Tau protein as a regulator of mitochondrial function and dynamics.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

A scalable, dividing cell model for the robust propagation and quantification of human sporadic Creutzfeldt-Jakob disease prions.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Epigenetic regulation of mesenchymal BMP signaling directs postnatal organ innervation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Single-shot wide-field biochemical imaging at 1 kHz frame rate.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Morphogenesis and topological evolution of a frustrated nematic liquid crystal under confinement.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

B cell-intrinsic CXCR3 drives efficient generation of ectopic pulmonary germinal center responses to influenza A virus infection.

Proceedings of the National Academy of Sciences of the United States of America·2026
查看所有相关文章

相关实验视频

Updated: Jan 18, 2026

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention
09:48

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention

Published on: September 11, 2017

10.3K

截然不同的前皮层组合编码响应执行和抑制.

Rajtarun Madangopal1, Yuan Zhao2, Conor Heins1

  • 1Behavioral Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224.

Proceedings of the National Academy of Sciences of the United States of America
|September 8, 2025
PubMed
概括
此摘要是机器生成的。

前极皮层 (PL) 用不同的神经元组合来执行和抑制动作. 这项研究表明,特定的PL合奏被招募用于学习行动和学习停止,从而实现行为灵活性.

关键词:
行为解码行为解码.灭绝的灭绝是一种灭绝.纵向体内活体成像的长度成像操作器学习是指操作器学习.恢复 恢复 恢复 恢复

更多相关视频

Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning
11:20

Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning

Published on: June 2, 2014

12.4K
Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning
08:43

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning

Published on: October 22, 2015

10.7K

相关实验视频

Last Updated: Jan 18, 2026

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention
09:48

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention

Published on: September 11, 2017

10.3K
Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning
11:20

Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning

Published on: June 2, 2014

12.4K
Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning
08:43

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning

Published on: October 22, 2015

10.7K

科学领域:

  • 神经科学是一个神经科学.
  • 行为神经科学 行为神经科学

背景情况:

  • 前皮质 (PL) 对于适应性行为至关重要,它将过去的经验与新信息相结合.
  • 一个稳定的PL神经元群体 (ensemble) 被招募用于操作奖励学习和响应执行.

研究的目的:

  • 研究PL神经元组合如何适应不断变化的奖励突发事件,特别是在灭绝 (奖励遗漏) 期间.
  • 为了确定相同的PL集团是否适应行为抑制,或者是否招募不同的集团进行灭绝学习.

主要方法:

  • 在操作条件 (训练),灭绝和恢复阶段,在老鼠中进行纵向单细胞成像.
  • 在PL活动模式上培训解码器,以预测试验明智的反应.
  • 使用in silico删除方法来识别用于响应执行和抑制的独特PL集.

主要成果:

  • 操作式灭绝学习招募了一个独特的PL Extinction组合用于响应抑制.
  • 训练和灭绝组合的协同参与编码了特定上下文的行为.
  • 两支乐团都重新投入工作,并在恢复期间保持各自的角色.

结论:

  • 前极皮层使用不同的神经元组合来对抗学习的关联 (动作执行与抑制).
  • 这些合奏的选择性招募使行为灵活性能够应对不断变化的环境突发事件.
  • 这突出了基于集合的神经编码,用于在同一大脑区域内多个甚至相互冲突的学习行为.