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Updated: Jan 18, 2026

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细胞外矩阵和纤维细胞激活在淋巴管状菌病

Alexander R Mukhitov1, Jilly F Evans2, Tiegang Han3

  • 1University of Pennsylvania Perelman School of Medicine, Department of Medicine, Philadelphia, Pennsylvania, United States.

American journal of respiratory cell and molecular biology
|September 8, 2025
PubMed
概括

一种名为RMC-5552的新药,通过向细胞外基质生产,在治疗淋巴管状菌病 (LAM) 方面表现有前途. 与目前的疗法不同,它抑制了对拉巴胺素不敏感的途径,可能为LAM患者提供更有效的治疗方法.

关键词:
淋巴血管菌病; 细胞外基质; mTORC1; TGF-b; Wnt/b-catenin; 细胞外基质; mTORC1; TGF-b; Wnt/b-catenin.

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